Endocrine Abstracts

Introduction and aim: Mean platelet volume (MPV) is a new important indicator of platelet activity in atherosclerosis. Elevated MPV is associated with the presence of more metabolically active platelets. The aim of our study is to evaluate whether change of MPV value is associated with cabergoline treatment in patients with prolactinoma.Materials and methods: Thirty patients with prolactinoma (mean age 33.4±8.5 years and body mass index (BMI): 28.1&...

Hashimoto’s thyroiditis is thought to result from the decreased of T helper type 2 (Th2) responses, leading to progressive destruction of thyrocytes. IFN-λ1, -λ2, and -λ3 (also known as IL-29, IL-28A, and IL-28B, respectively) is a recently described member of the IFN-λ family and has been shown to decrease production of Th2 cytokines in vitro. However, the role and mechanism of IFN-λ1 in Hashimoto’s thyroiditis remain unkno...

Introduction: We aimed to investigate the conjunctival surface changes in Hashimoto’s thyroiditis (HT) patients and controls comparatively, and search the correlation of these changes with thyroid functions and thyroid autoantibody level in patients without thyroid associated ophthalmopathy (TAO).Methods: A total of 25 patients with HT and 33 healthy individuals were enrolled in the study. Serum TSH, fT4 and fT3 level, and anti...

Introduction: Patients that were suspected to have thyroid agenesis on imaging procedures were retrospectively evaluated.Methods: Totally 4155 patients had scintigraphy imaging between years of 2010–2015 in our university. 4021 (96.77%) patients were adults (>18 years) and 134 patients (3.22%) were in the pediatric population. Among adult population, 3060 (76.1%) were female, and 1095 (27.2%) were male. In the pediatric population, 85 (63.4%) pa...

Introduction: Thyroid papillary carcinomas originate from thyroid follicular epithelia and are the most frequent thyroid differentiated carcinomas. Medullary thyroid carcinomas originate from thyroid parafollicular C cells and %25 are a component of Multiple Endocrine Neoplasia (MEN) syndromes. Co-incidence of the two condition on the same patient is so rare.Case: 78 years old female patient who has had simple goiter for 10 years, was investigated about ...

Introduction: Differentiated thyroid carcinomas (DTC) are originated from thyroid follicular epithelial cells and comprises %90 of all thyroid carcinomas. Researches indicate that sorafenib is more efficacious than other chemotherapeutic agents on metastatic iodide refractory DTCs.Material and methods: In our center, between 2013 and 2015, sorafenib was applied to six patients who had iodide refractory metastatic DTC. Five of the patients were female. Th...

Objective: Polycystic ovary syndrome (PCOS) is associated with insulin resistance, central obesity and dyslipidaemia. Furthermore, abnormal aminotransferase activity is common in women with polycystic ovary syndrome. The aim of this study is to assess the γ-glutamyltranspeptidase (GGT) and alanine aminotransferase (ALT) levels in women with PCOS in whom non-alcoholic fatty liver disease was excluded by history, serum testing and abdominal ultrasonography.<p class="abs...

Objective: The objectives of this study were to determine the prevalence of diagnosed and undiagnosed diabetes mellitus (DM), prediabetes and to evaluate the associated risk factors in the sample of adult Turkish population.Methods: A total of 4000 eligible study subjects aged 20 years or older, chosen by multistage sampling on a field were selected. Of those 3721 subjects (2139 women and 1582 men) participated in the study. The study was performed betwe...

Objective: Aspergillosis is defined as the infection of the Aspergillus type mold and is commonly seen in hematologic malignancies, hematopoietic stem cell transplantation, aplastic anemia, primary immunodeficiency, and immunocompromised patients. Fungal sinusitis in diabetes mellitus is generally presented as rhinoorbitocerebral involvement of mucormycosis. Herein, a fungal sinusitis caused by Aspergillus case presented with headache is reported.<p class...

Objective: The frequency of differentiated thyroid cancer in the Graves’ disease are controversial. The aim of this study was to evaluate the frequency of thyroid cancers in patients operated because of Graves’ disease.Subjects and methods: Sixty-six patients in whom thyroidectomy was performed because of Graves’ disease between 2001 and 2012 were evaluated retrospectively. Patients who had received radioactive iodine treatment and externa...